Ethylbenzene (anaerobic)

Starting: Ethylbenzene
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📊 Pathway Information

Description:
Ethylbenzene is one of the most water soluble aromatic hydrocarbons. Under aerobic conditions ethylbenzene degradation involves oxygenase reactions. Anaerobic ethylbenzene mineralization under denitrifying conditions was demonstrated for pure bacterial cultures ([http://www.ncbi.nlm.nih.gov/pubmed/7710331|Rabus and Widdel 1995], [http://www.ncbi.nlm.nih.gov/pubmed/8824622|Ball et al., 1996], and [http://www.ncbi.nlm.nih.gov/pubmed/15687214|Kuehner et al., 2005]). Anaerobic degradation of ethylbenzene is initiated by a dehydrogenation of ethylbenzene to 1-phenyl ethanol, and subsequent conversion to benzoate (or benzoyl-CoA). Benzoate (or benzoyl-CoA) is a central intermediate in anaerobic degradation of a variety of aromatic hydrocarbons. The pathway for anaerobic ethylbenzene oxidation to benzoate is based on [http://www.ncbi.nlm.nih.gov/pubmed/15687214|Kuehner et al., 2005]. The source of metabolic energy for acetophenone carboxylation is hydrolysis of ATP ([http://www.ncbi.nlm.nih.gov/pubmed/20047908|Jobst et al., 2010]).
Total Reactions: 6
Unique Compounds: 7
Starting Compound: Ethylbenzene
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