3-Methylquinoline

Starting: 3-Methylquinoline
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📊 Pathway Information

Description:
3-Methhylquinoline can be found in groundwater near landfills containing azaarene contaminated wastes, near creosote wood preservation facilities, in aquifers affected by fossil fuel processing activities and in shale oil. This compound is a known carcinogen causing various health effects and environmental damage, thus its environmental fate and biodegradation is important ([http://www.ncbi.nlm.nih.gov/pubmed/8489738|Schach et al., 1993]). Comamonas testosteroni 63, from activated sludge, is known to degrade 3-methylquinoline to 2,5,6-trihydroxy-3-methylpyridine. This compound is degraded further to unknown products ([http://www.ncbi.nlm.nih.gov/pubmed/8489738|Schach et al., 1993]). Quinoline, the unsubstituted derivative of 3-methylquinoline, is degraded by Rhodococcus strain B1 in a similar manner to form 5-hydroxy-6-(3-carboxyoxopropenyl)-1H-2-pyridone, which is further degraded to unknown metabolites ([http://www.ncbi.nlm.nih.gov/pubmed/2514722|Schwarz et al., 1989]).
Total Reactions: 8
Unique Compounds: 8
Starting Compound: 3-Methylquinoline
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